Subgroups of dm of interest to the oral and maxillfacial surgeon.
|DM with anti-NXP2 antibodies|
|These patients have a heightened association with the development of malignancy.
Presence of severe dysphagia further worsens prognosis due to the risk of aspiration pneumonia, making oral healthcare impossible in the dental office
More common in adult DM than JDM.
Associated with a poor prognosis as 37.5% of patients with these antibodies develop advanced malignancy within 3 years of their appearance.
|DM with anti-TIF-1γ antibodies|
|These patients are associated with an increased risk of developing malignancy as 50–70% of them develop cancer
Ovoid palatal patch observed in 40% patients, making it a probable clinical indicator of the presence of a systemic malignancy.
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