Open Access
Table 1
Differential criteria between papilloma, irritational fibroma and giant cell fibroma.
| Criterion | Papilloma | Irritative fibroma | Giant cell fibroma |
|---|---|---|---|
| Surface appearance | Exophytic growth, cauliflower-like surface | Smooth, homogeneous surface | Smooth, somestimes similar to papilloma (exophytic, lobulated) |
| Location | Tongue and palate (60%) according to Frigerio et al. (125/207 cases) | Buccal mucosa (60%) according to de Santana Santos et al. [12] | Gingiva, masticatory muccosa (Regezi et al.) [5] |
| Transmissible disease | Yes (associated with HPV, mainly types 6/11) | No | No |
| Oncogenic potentiel | None (benign lesions, not linked to high-risk HPV) | None | None |
| Recurrence | Rare if completely excised | Rare if irritative cause is removed | Very rare |
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