J Oral Med Oral Surg
Volume 24, Number 3, October 2018
|Page(s)||107 - 111|
|Section||Article original / Original article|
|Published online||10 October 2018|
Assessing the effectiveness of botulinum toxin injections into masticatory muscles in the treatment of temporomandibular disorders
Department of Maxillofacial Surgery and Stomatology, Angers University Hospital,
2 Departement of Maxillofacial Surgery and Stomatology, Nantes University Hospital, Nantes, France
3 Department of Maxillofacial and Facial Plastic Surgery, Tours University Hospital, Tours, France
* Correspondence: firstname.lastname@example.org
Accepted: 10 January 2018
Introduction: Temporomandibular disorders (TMD) are a common and invalidating disease sometimes difficult to treat. Current international recommendations favour reversible and non-invasive treatments, including the injection of botulinum toxin (BTX) into masticatory muscles. There is no strong evidence of its effectiveness. Objective: The main goal of this study was to assess the effectiveness of BTX six months following injection, in terms of pain, mouth opening, improvement of symptoms and duration of effect. Materials and methods: A retrospective study carried out at Nantes University Hospital between 2014 and 2016. Results: Thirty-four patients were included. The mean age was 37 years (17–76) and seventy six percents were female. Eighty percent of patients reported a significant improvement, notably in cases of arthralgia, which decreased in 8/18 (44%) patients (p < 0.05). The mean duration of measured efficacy was 4.2 months. Discussion: Significant improvement in cases of arthralgia and a tendency for improvement in cases of myalgia, with a mean duration of action of 4.2 months. Although BTX injection do not guarantee complete resolution of myofascial pain, it have been shown to have beneficial effects on some symptoms have been shown. Conclusion: Botulinum toxin should be considered as an alternative treatment when other conservative methods fail to yield satisfactory results. A thorough multicentre assessment is necessary in the future to scientifically validate its use.
Key words: temporomandibular disorder / botulinum toxin injection / effectiveness
© The authors, 2018
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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