Up-to Date Review And Case Report

Adenosquamous carcinoma, a rare and unknown tumor

¹ Paul Sabatier University, Dental Faculty, CHU Toulouse, France
² INSERM U1043, Université Toulouse III CHU Purpan, BP 3028, 31024 Toulouse, France
³ Department of Oral surgery, Dental Faculty, Université Paul Sabatier, Centre hospitalo-universitaire de Toulouse, 31062 Toulouse, France
⁴ Otorhinolaryngology Department, 24 Chemin de Pouvourville, 31400 Toulouse, France
⁵ Pathology Department, 1 Av. Irene Joliot-Curie, 31100 Toulouse, France
⁶ Université de Toulouse, UPS, INP, LAPLACE, 118 route de Narbonne, 31062 Toulouse, France

^* Correspondence: benat.g@chu-toulouse.fr

Received: 1 June 2017
Accepted: 26 December 2017

Abstract

Introduction: Adenosquamous carcinoma (ASC) of the head and neck is a rare malignant tumor, with one hundred cases diagnosed so far in the literature. Observation: A 66 years old female patient had a ASC of the right posterior floor of the mouth with a classification T1N0M0. Treatment consisted of surgical management and active surveillance. Discussion: Through this case report, we present this type of tumor and we discuss the main differential diagnosis from a clinical and histological point of view. Conclusion: This entity was described for the first time in 1968 by Gerughty. The CAS is defined by the World Health Organization as “a tumor of the upper respiratory tract, with two distinct squamous and glandular components.” The CAS is considered as an aggressive tumor with a redoubtable prognosis should not be ignored.