Open Access
Table II
Expression patterns of P53 and associated markers in histological subtypes of ameloblastoma.
| Study | Histological variant | P53 expression rate | Co-expressed markers | Potential prognostic implications |
|---|---|---|---|---|
| Noorieh Sharifisistani et al. (2011) [7] | Follicular/Plexiform AMB | Higher in follicular variant | Ki-67 | More aggressive behavior in follicular variant |
| Amol Ramchandra Gadbail et al. (2011) [8] | SMA | High | Bcl-2, Bax | Aggressiveness, recurrence |
| Zulfin Shaikh et al. (2015) [11] | AA | Variable, mostly peripheral staining | Ki-67 | Associated with proliferative activity |
| Adriano Mota Loyola et al. (2016) [12] | AMECA | Very high | Ki-67, MDM2 | Malignancy |
| Zhu You et al. (2019) [13] | AM-BC | High | Ki-67 | Aggressiveness |
| Jefferson-da Rocha Tenório et al. (2018) [14] | Various AMB subtypes (follicular, plexiform, unicystic) | Moderate | Bcl-2, Bax | Anti-apoptotic profile due to Bcl-2/Bax imbalance |
| Abhishek Singh et al. (2020) [15] | SMA/OKC | High in SMA, Higher in OKC | MDM2 | Progression potential |
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