Open Access

Table I

Studies included in the literature review.

Case and year Age/gender Comorbidity Malignancy (Cancer type) Medication At Time of presentation Previous medication Initial symptoms and examination Localisation Treatment
Pennings et al. (2023) [3] 44 yo / F None Hodgkin lymphoma,
Nodular sclerosis subtype,
Metastatic
Pembrolizumab, GVD Doxorubicin, Bleomycin,
Vinblastine,
Dacarbazine (2017 to 2021)
Pain, Dental mobility,
Swelling
Mandible Right lingual area : Torus Chlorexhidine rinse + oral hygiene, Bone smoothening, Sequestrotomy
Decaux et al. (2020) [4] 28 yo / F None Metastatic melanoma (stage IIIB) Pembrolizumab, Epadocast Interferon (2014 to 2015) Pain, bleeding,
Swelling,
slight inflammation
Maxilla : posterior right side Antibiotherapy, root canal treatment, chlorexhidine + hydrogen peroxide rinse, sequestrotomy + tooth extraction
Patel et al. (2023) [5] 73 yo / M Asthma, Hypertension,
Gastro-esophageal reflux,
Smoker
Melanoma (stage 3) Pembrolizumab, Losartan,
Amlodipine, Omeprazole,
Ventolin,
Tadalafil
  Pain, Bone exposure Mandible right lingual area : Torus Oral hygiene
Myoken et al. (2020) [6] 69 yo / F Not available Metastatic NSCLC (stage IVB) Pembrolizumab + Denosumab   Pain, swelling,
bleeding,
purulent discharge
Mandible : posterior left side Antibiotherapy, Local injection of minocylcine + hydrochloride, teeth extraction Sequestrotomy / surgical curettage, nasolabial flap reconstruction

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