Open Access

Table I

Characteristics of the included studies comparing adjacent second molar periodontal health.

Author Objective Study design Number of subjects Mean age ± Standard deviation
(Min–Max)
Study duration
Ahmad M, 2021 To compare the influence of two flap designs on the periodontal status of M2 Randomized controlled trial 60 23.22 ± 3.17 6 months
Alqahtani NA, 2017 To compare the influence of two flap designs on post-operative outcomes and the periodontal status of M2 Randomized, split-mouth cross-over comparative study 60 (18–41) 3 months
Aniko-Włodarczyk M, 2021 To evaluate the effect of M3 removal on the periodontal status of M2 Interventional, prospective study 60 24. 82 ± 5.51 2 months
Baldini N, 2015 To compare the influence of two flap designs on the periodontal status of M2 Randomized, single-blinded, comparative and prospective study 52 37.8
(18– 46)
6 months
Baqain ZH, 2012 To compare the influence of two flap designs on post-operative outcomes and the periodontal status of M2 Randomized, split-mouth cross-over, comparative, prospective study 19 21.4 ± 2.3 4 months
Briguglio F, 2011 To compare the influence of three flap designs on post-operative outcomes and the periodontal status of M2 Randomized, double-blinded, comparative and prospective study 45 (18–41) 24 months
Desai A, 2014 To compare the influence of two flap designs on post-operative outcomes and the periodontal status of M2 Randomized, interventional, comparative and prospective study 30 25
(20– 30)
15 days
Dicus-Brookes C, 2013 To assess the impact of M3 removal on the periodontal status of M2 Interventional, prospective study 69 21.8
(20–25)
3 months
Fakour SR, 2017 To compare the influence of two flap designs on the periodontal status of M2 Randomized, single-blinded, split-mouth cross-over comparative study 25 42.8 ± 3.2 2 months
Faria AI, 2012 To compare the influence of two flap designs on post-operative outcomes and the periodontal status of M2 Interventional, prospective study 25 21.03 ± 4.38 12 months
Kim H-R, 2011 To compare the influence of flap and flapless extractions of M3 on post-operative outcomes and the periodontal status of M2 Randomized, split-mouth cross-over, comparative, prospective study 30 27
(19–49)
3 months
Korkmaz YT, 2015 To compare the influence of two flap designs on post-operative outcomes and the periodontal status of M2 Randomized, single-blinded, split-mouth cross-over comparative and prospective study 28 22.43 ±3.02
(18–28)
3 months
Laurito D, 2016 To compare the influence of two flap designs on post-operative outcomes and the periodontal status of M2 Interventional, prospective study, double blind 24 22.42 ±3.45 2 months
Melo Stella PE, 2017 To evaluate the effect of M3 removal on the periodontal status of M2 Interventional, prospective study 23 20.3 6 months
Montero J, 2011 To assess the impact of M3 removal on the periodontal status of M2 Interventional, prospective study 48 23.01 12 months
Mudjono H, 2020 To compare the influence of two flap designs on the periodontal status of M2 Prospective, split-mouth study 15 (19–26) 1 month
Ottria L, 2017 To assess the impact of M3 removal on the periodontal status of M2 comparing three flap designs Interventional, prospective study 150 (14–21) 3 months
Passarelli PC, 2019 To assess the impact of M3 removal on the periodontal status of M2 Interventional, prospective study 89 35 ± 18.7
(18–81)
6 months
Petsos H, 2016 To assess the impact of M3 removal on the periodontal status of M2 Interventional, prospective study 78 16 ± 2 6 months
Pham T, 2019 To assess the impact of M3 removal on the periodontal status of M2 Interventional, prospective study 38 21.89 ± 2.74 6 months
Silva JL, 2011 To assess the impact of M3 removal on the periodontal status of M2 comparing two flap designs Split-mouth cross-over, comparative, prospective study 24 23
(14–33)
3 months
Sridharan G, 2020 To compare the influence of two flap designs on post-operative outcomes and the periodontal status of M2 Randomized, single-blinded, split-mouth cross-over comparative study 25 26.5
(18–35)
1 month
Tabrizi R, 2013 To assess the impact of M3 removal on the periodontal status of M2 Interventional, prospective study 50 20.9
(18–25)
6 months

M2: second molar.

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