Open Access
Table I
Clinicopathological features of ameloblastoma and recurrence rate.
| Sl No |
Author | No of cases | Avg Age in years |
Gender | Location | Radiographic features | Diagnosis | Treatment | Avg time after T/t | Contributing Factors For Recurrence | Recurrence Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Hertog (2010) [5] | 25 8/20 (5 year follow up) |
34.4 | Males-14 Females-11 |
Mandible-20 Maxilla-5 |
Follicular- 10 Plexiform- 7 |
Conservative- 17 Radical-8 |
5 years | 53% Conservative-8/15 Radical-None |
||
| 2 | Zhang et al. (2010) [6] | 10/37 | 14.8 (all <18) |
Males −23 Females- 14 | Mandible (100%) |
Multilocular 16 cases (16/37, 43.2%), Unilocular- 21 (56.8%) |
Unicystic −9 Solid-28 Follicular- 18 cases (48.7%), Plexiform − 4 |
Conservative −29 (78.4%, 7 unicystic, 22 solid type) Radical −8 (21.6%, 6 solid and 2 unicystic type) |
3 months to 6 years |
Conservative treatment | 27% (9 −solid type, 1 − unicystic type.) |
| 3 | Siar et al. (2012) [7] | 340 18/135 |
Male-197 Female- 143 |
Mandible- (n 311/340, -91.5%). Maxilla 29 |
Multilocular radiolucencies (36.8%) | Unicystic ameloblastomas- 95 (28%) SMA- 221 (65%) Desmoplastic ameloblastoma, 22 (6.4%) and peripheral ameloblastomas-2 (0.6%) |
Enucleation (n 42/92, 45.7%) |
18 /135 cases (13.3%) 6 UAs (26.1%) and 17 SMAs (73.9%) |
|||
| 4 | Antonoglou (2014) [8] | 35/229 | NA | Mandible −141 Maxilla-2 NA:86 |
Multicystic −129 Unicystic −98 |
Unicystic- Radical-4% Conservative-17% Solid or multicystic Radical −8% Conservative–38% |
|||||
| 5 | Seintou et al. (2014) [9] | 15/ 51 | 12.7 (<16) |
Males −25 Females-26 |
44(86.3%)Mandible | Root resorption, 36 (70.6%) were unilocular, three (5.9%) were multilocular, |
Unicystic ameloblastoma | Enucleation or enucleation–curettage- 31/51, 60.8%. Margin resection-3 (5.9%) |
4.4 years | Conservative approach with enucleation or excision |
Recurrence: 29.4% (All cases were treated with enucleation or excision) |
| 6 | Bansal et al. (2015) [10] | 1/39 | 13.6 (<18) |
Males −26 Females-13 |
Mandible (97.4%); | Multilocular radiolucencies in 12/ 39 cases (30.7%) and unilocular radiolucencies in 23 (59.0%); one case (2.6%) showed a mixed radio-opaque/radiolucent lesion |
Solid variant-20 of 39 cases (51.3%) Unicystic- 19 (48.7%) Follicular −4 Plexiform −16 |
Conservative surgical treatment (enucleation plus peripheral ostectomy) 18 (5 solid, 13 unicystic) Resection (segmental or hemi-mandibulectomy and bone graft/ surgical plates) 15 (12 solid, 3 unicystic) |
11 years | Conservative treatment | 2.6% |
| 7 | Singh T et al. (2015) [11] | 6/41 | 43 | Males −26 Females- 15 |
Mandible 33 (80.5%) compared to the maxilla- 8(19.5%) |
SMA most common subtype (34 cases), followed by the UA (6 cases). |
SMA-30(85.3%) radical treatment (surgical resection), 4 14.7% treated conservatively UA- cons 4(66.7%) rather than with surgical resection 2(33.3%). |
8.5 years | SMA: 14.7% Conservative T/t −60% Radical T/t- 6.9% UA- 33.3%(2) |
||
| 8 | Almeida (2016) [4] | 116/394 | 37 | Males −179 Females- 215 |
Mandible (90%) | Multicystic 66/116 were follicular ameloblastoma, 21/116 were plexiform ameloblastoma |
Cons −245 Rad-149 |
Within 5 years | 29.4% Conservative T/t − 98(40%) Radical T/t-18(12%) |
||
| 9 | Milman (2016) [12] | 16/23 | 56 | Males-19 Females-4 |
Maxilla with orbital extension | Follicular (45%) and plexiform(41%) Basal cell like(9%) and mixed (4.5%) |
Conservative T/t −14 Radical T/t −7 |
3.8 years | Recurrence-70% Conservative T/t-57% Radical T/t-29% |
||
| 10 | Laborde A et al. (2017) [13] | 9/27 | 46.3 ±17.4 | 17 Males-17 Females-7 |
Mandible: 20 patients (74.1%) Maxilla 7 |
– | Follicular (29.6%) and plexiform (22.2%) MC-10 UC-15 |
Recurrence: Conservative treatment 22 and Radical treatment 14 case | –- | Conservative treatment | 33% |
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