Clinical and pathological characteristics of benign spindle cell tumors.
|Solitary myofibroma||Fibromatosis||Nodular fasciitis||Solitary fibrous tumor|
|Age Predilection||Up to 4th decade||Children & young Adults||20–40 years||Adults|
|Intraoral site||Mandible||Paramandibular soft tissue||Buccal mucosa|
|Cellular component||Plump spindle-shaped cells with eosinophilic cytoplasm||Plump spindle-shaped cells, more cellular at periphery||Plump spindle-shaped cells||Round to spindle|
|Arrangement||Biphasic||Long Streaming fascicles||Tissue culture/feathery||Short fascicles to patternless|
|Stromal Characteristics||Hyalinized at periphery||Variable amounts of collagen||Myxoid (early) to hyalinised (long-standing)
|Vascularity||HPC-like vascular pattern||Thin walled vessels||Haemorrhagic areas with hemosiderin deposition||Focal HPC-like vascular pattern|
|Inflammation||Absent||Scattered lymphocytes at periphery||Scattered lymphocytes in centre||Absent|
|Alcian blue stain||Negative||Negative||Stroma is Positive||Negative|
|β-Catenin||–||+++ (nuclear)||–||+++ (nuclear)|
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