J Oral Med Oral Surg
Volume 29, Number 2, 2023
|Number of page(s)||5|
|Published online||19 June 2023|
Original Research Article
Correlation between number of dental amalgam restorations and severity of oral mucositis after head-neck radiotherapy
Department of Oral and Maxillofacial Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Department of Endodontics, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran
3 Department of Oral and Maxillofacial Medicine, School of Dentistry, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Radiotherapy, School of Medicine, Radiation Oncology Research Center, Cancer Institute, Imam khomeini Hospital, Tehran University of medical Sciences, Tehran, Iran
5 Department of Oral Medicine, Dental Faculty, Shahid Beheshti University of Medical Sciences, Tehran, Iran
* Correspondence: firstname.lastname@example.org
Accepted: 16 May 2023
Background: Head and neck radiotherapy causes side effects such as stomatitis. In vitro studies demonstrated local dose enhancement due to backscatter radiation near metal restorations. The aim of this study was to analyze correlation between number of amalgam restorations with severity of oral mucositis in patients with head and neck radiotherapy. Method and materials: This cross-sectional study was accomplished on 80 patients under head and neck radiotherapy referred to Cancer Institute (Tehran, Iran) in 2014–2015. Severity of mucositis and pain were measured by three examinations according to WHO criteria and visual analogue scale. Descriptive statistics and Spearman's correlation coefficient test used to analyze the data by IBM SPSS statistics V22.0. Results: There was no significant correlation between the number of amalgam restorations and severity of mucositis and pain on second and third examinations. However, severity of mucositis and pain were found to be significantly correlated with radiation dose per session (p = 0.013, rs = 0.276), (p = 0.032, rs = 0.240) and total radiation dose (p < 0.001 rs = 0.393), (p < 0.001, rs = 0.445) on second and third examinations respectively. Conclusion: This study showed that number of dental amalgam restorations have no impact on aggravation of oral mucositis caused by head and neck radiotherapy.
Key words: Radiotherapy / mucositis / dental amalgam / cancer / oral mucosa
© The authors, 2023
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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