J Oral Med Oral Surg
Volume 26, Number 1, 2020
|Number of page(s)||4|
|Section||Cas clinique / Short case report|
|Published online||03 February 2020|
Short Case Report
A non-syndromic case of maxillo-mandibular keratocysts
Département de Chirurgie Orale Service Odontologie [Department of Oral Surgery and Odontology], Hôpital Pitié-Salpêtrière-Paris, Paris, France
2 Service d'Anatomo-Pathologie [Pathology Department], Hôpital Pitié-Salpêtrière-Paris, Paris, France
3 UFR Odontologie [UFR Odontology], Université Paris Descartes, Paris, France
4 UFR Odontologie [UFR Odontology], Université Paris Diderot, Paris, France
* Correspondance: firstname.lastname@example.org
Accepted: 27 September 2019
Introduction: Odontogenic keratocysts (OKCs) are frequent, aggressive lesions with a strong tendency to recur, particularly in their para-keratinized majority form. Although they are mainly non-syndromic, these lesions are found in a large majority of patients with Gorlin syndrome. Thus, multiple forms are almost always associated with this syndrome and require investigation to prevent the risk of various cancers. Non-syndromic multiple forms are exceptional. Observation: A 20-year-old patient presented with dual localization of maxillary and left mandibular OKC at consultation. Under general anesthesia, excision of the lesions and extraction of the impacted wisdom teeth 28 and 38 were performed. The patient showed no clinical sign of Gorlin syndrome. Discussion: The OKC or epidermoid cyst is derived from the dental lamina or its remnants and from the basal part of the oral epithelium and represents between 10 and 20% of all cystic lesions in the maxillae. Its peak of incidence is between the second and fourth decade (or earlier in case of association with basal cell necrosis). OKC occurs mainly in the mandible and preferentially at the Ramus, where its frequency can reach 70% depending on the series. Conclusion: The management of OKC by oral surgeons must be conducted in a multidisciplinary setting in close collaboration with dermatologists, geneticists, and anatomic pathologists. Due to the strong recidivating character of OKCs, patient monitoring is essential.
Key words: odontogenic keratocyst / non-syndromic
© The authors, 2020
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