| Issue |
Med Buccale Chir Buccale
Volume 13, Number 2, 2007
|
|
|---|---|---|
| Page(s) | 103 - 106 | |
| Section | Communication brève | |
| DOI | https://doi.org/10.1051/mbcb/2007006 | |
| Published online | 18 November 2009 | |
Etude électrophysiologique préliminaire sur la régénération du nerf mentonnier après écrasement chez le rat
Electrophysiological preliminary study of mental nerve regeneration after a crush lesion in rat
1
Faculté de Chirurgie dentaire, Université de Lille II, place de Verdun, 59000 Lille
2
Inserm Unité 595, Faculté de Chirurgie dentaire, Université Louis Pasteur, 11 rue Humann, 67085 Strasbourg Cedex
La régénération du nerf mentonnier après écrasement et pose d’une membrane, constituée de polyélectrolytes et fonctionnalisée par le Nerve Growth Factor (NGF), est évaluée chez le rat à l’aide d’enregistrements électrophysiologiques. Le NGF semble faciliter la régénération. Med Buccale Chir Buccale 2007 ; 13 : 103-106.
Abstract
This preliminary study aims to test if a multilayered polyelectrolyte membrane functionalized with Nerve Growth Factor (NGF) improves the regeneration of the mental nerve after a crush lesion in rat. Neurograms were recorded before lesion, immediately after and one month after the lesion in two groups of injuried rats: one group without membrane (n=10) and one group with the membrane functionalized with NGF wrapped around the wounded nerve (n=10). This novel support seems to facilitate mental nerve regeneration one month after the crush. Med Buccale Chir Buccale 2007 ; 13 : 103-106.
Mots clés : régénération / nerf mentonnier / facteur de croissance nerveux
Key words: regeneration / mental nerve / nerve growth factor
© SFMBCB, 2007
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