Open Access
Educational Article
J Oral Med Oral Surg
Volume 27, Number 2, 2021
Article Number 21
Number of page(s) 9
Published online 15 January 2021
  1. Pober BR. Williams-Beuren syndrome. N Engl J Med. 2010;362:239–52. [CrossRef] [PubMed] [Google Scholar]
  2. Online Mendelian Inheritance in Man. #194050. Johns Hopkins University. Available from (accessed on 27 May 2020). [Google Scholar]
  3. Castro T, de Paula Martins Santos C, de Oliveira Lira Ortega A, Gallottini M. Oral characteristics and medical considerations in the dental treatment of individuals with Williams syndrome. Spec Care Dentist. 2019;39:108–113. [CrossRef] [PubMed] [Google Scholar]
  4. Shin J, Lee J. Considerations for dental treatment of Williams syndrome patients. J Korean Acad Oral Health. 2018;42:238–241. [CrossRef] [Google Scholar]
  5. Moskovitz M, Brener D, Faibis S, Peretz B. Medical considerations in dental treatment of children with Williams syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endodontol. 2005;99:573–580. [CrossRef] [Google Scholar]
  6. Online Mendelian Inheritance in Man. #194050. Johns Hopkins University. Available from (accessed on 27 May 2020). [Google Scholar]
  7. Gray III JC, Krazinski AW, Schoepf UJ, Meinel FG, Pietris NP, Suranyi P, et al. Cardiovascular manifestations of Williams syndrome: imaging findings. Journal of cardiovascular computed tomography. 2013;7:400–407. [CrossRef] [PubMed] [Google Scholar]
  8. Sammour ZM, Gomes CM, de Bessa Jr J, Pinheiro MS, Kim CA, Hisano M, et al. Congenital genitourinary abnormalities in children with Williams–Beuren syndrome. J Pediatr Urol. 2014;10:804–809. [CrossRef] [PubMed] [Google Scholar]
  9. Copes LE, Pober BR, Terilli CA. Description of common musculoskeletal findings in Williams Syndrome and implications for therapies. Clin Anat. 2016;29:578–589. [CrossRef] [PubMed] [Google Scholar]
  10. Mass E, Belostoky L. Craniofacial morphology of children with Williams syndrome. Cleft-Palate Craniofac J. 1993;30:343–349. [CrossRef] [Google Scholar]
  11. Dogan OA, Kiper PO, Utine GE, Alikaşifoglu M, Boduroglu K. A diagnosis to consider in an adult patient with facial features and intellectual disability: Williams syndrome. Korean J Fam Med. 2017;38:102. [CrossRef] [PubMed] [Google Scholar]
  12. Pereira L, Soares DN, de Lima Pedro R, da Silva Fidalgo TK, Costa MC, de Araújo Castro GF. Orofacial findings and dental management of a child with Williams syndrome. Revista Odonto Cienc. 2016;31:41–44. [Google Scholar]
  13. Torres CP, Valadares G, Martins MI, Borsatto MC, Díaz-Serrano KV, Queiroz AM. Oral findings and dental treatment in a child with Williams–Beuren syndrome. Braz Dent J. 2015;26:312–316. [CrossRef] [PubMed] [Google Scholar]
  14. Maritsi D, Kossiva L, Vartzelis G. Williams syndrome with a “twist”. Case Rep Med. 2010;2010:726845. [Google Scholar]
  15. Cingano L, Servetto R, Loria P, Calcagno E. Odontostomatological aspects in patients with Williams syndrome: a series of 4 cases. Minerva Stomatol. 2013;62:447–54. [PubMed] [Google Scholar]
  16. Chonan M, Kanamori M, Kumabe T, Saito R, Tominaga T. Pilomyxoidastrocytoma of the cerebellum with Williams syndrome: a case report. Childs Nerv Syst. 2013;29:1211–1214. [CrossRef] [PubMed] [Google Scholar]
  17. Tekendo-Ngongang C, Dahoun S, Nguefack S, Gimelli S, Sloan-Béna F, Wonkam A. Challenges in clinical diagnosis of Williams-Beuren syndrome in sub-Saharan Africans: case reports from Cameroon. Mol Syndromol. 2014;5:287–292. [CrossRef] [PubMed] [Google Scholar]
  18. Campos-Lara P, Santos-Diaz MA, Ruiz-Rodríguez MS, Garrocho-Rangel JA, Pozos-Guillén AJ. Orofacial findings and dental management of Williams-Beuren syndrome. J Clin Pediatr Dent. 2012;36:401–404. [CrossRef] [PubMed] [Google Scholar]
  19. Morris CA. Williams Syndrome. 1999 Apr 9 [Updated 2017 Mar 23]. In: Adam MP, Ardinger HH, Pagon RA, et al. (editors). GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2020. Available from [Google Scholar]
  20. Manning M, Professional HL. Practice and Guidelines Committee. Array-based technology and recommendations for utilization in medical genetics practice for detection of chromosomal abnormalities. Genet Med. 2010;12:742–745. [CrossRef] [PubMed] [Google Scholar]
  21. Xia Y, Huang S, Wu Y, Yang Y, Chen S, Li P, Zhuang J. Clinical application of chromosomal microarray analysis for the diagnosis of Williams–Beuren syndrome in Chinese Han patients. Mol Genet Genom Med. 2019;7:e00517. [CrossRef] [Google Scholar]
  22. Committee on Genetics. Health care supervision for children with Williams syndrome. Pediatrics. 2001;107:1192–1204. [PubMed] [Google Scholar]
  23. Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP 3rd, Fleisher LA, et al. AHA/ACC Focused Update of the2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: a Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation 2017;135:e1159-e1195. [Google Scholar]
  24. ADA. Antibiotic prophylaxis prior to dental procedures. Oral Health Topics 2017 [cited 31st March 2017]; Available from [Google Scholar]
  25. Bird LM, Billman GF, Lacro RV, Spicer RL, Jariwala LK, Hoyme HE, et al. Sudden death in Williams syndrome: report of ten cases. J Pediatr. 1996;129:926–931. [CrossRef] [PubMed] [Google Scholar]
  26. Collins II RT, Collins MG, Schmitz ML, Hamrick JT. Peri-procedural risk stratification and management of patients with Williams syndrome. Congenit Heart Dis. 2017;12:133–142. [CrossRef] [PubMed] [Google Scholar]
  27. Lourenço M, Azevedo A, Brandao I, Petit C, Jung S, Huck O. Orofacial manifestations in outpatients with anorexia nervosa and bulimia nervosa focusing on the vomiting behavior. Clin Oral Invest. 2018;22:1915–1922. [CrossRef] [Google Scholar]
  28. Waldron C, MacGiolla Phadraig C, Nunn J, Comiskey C, Swift DE, Guerin S, et al. Oral hygiene programmes for people with intellectual disabilities. Cochrane Database Syst Rev. 2017;2017:CD012628. [Google Scholar]
  29. American Academy on Pediatric Dentistry Clinical Affairs Committee Behavior Management Subcommittee; American Academy on Pediatric Dentistry Council on Clinical Affairs. Guideline on behavior guidance for the pediatric dental patient. Pediatr Dent. 2011-2012;33:161–173. [Google Scholar]
  30. Royston R, Howlin P, Waite J, Oliver C. Anxiety disorders in Williams syndrome contrasted with intellectual disability and the general population: a systematic review and meta-analysis. J Autism Dev Disord. 2017;47:3765–3777. [CrossRef] [PubMed] [Google Scholar]
  31. Poornima P, Patil PS, Subbareddy VV, Arora G. Dentofacial characteristics in William's syndrome. Contemp Clin Dent. 2012;3:S41. [CrossRef] [PubMed] [Google Scholar]
  32. Yamaguchi T, Shirota T, Adel M, Takahashi M, Haga S, Nagahama R, et al. Orthodontic treatment and maxillary anterior segmental distraction osteogenesis of a subject with Williams–Beuren Syndrome and isolated cleft palate: a long-term follow-up from the age of 5 to 24 years. Case Rep Dent. 2017;2010:7019045. [Google Scholar]
  33. Axelsson S, Bjørnland T, Kjaer I, Heiberg A, Storhaug K. Dental characteristics in Williams syndrome: a clinical and radiographic evaluation. Acta Odontol Scand. 2003;61:129–136. [CrossRef] [PubMed] [Google Scholar]
  34. Wong D, Ramachandra SS, Singh AK. Dental management of patient with Williams syndrome − a case report. Contemp Clin Dent. 2015;6:418–420. [CrossRef] [PubMed] [Google Scholar]
  35. Urban Z, Peyrol S, Plauchu H, Zabot MT, Lebwohl M, Schilling K, et al. Elastin gene deletions in Williams syndrome patients result in altered deposition of elastic fibers in skin and a subclinical dermal phenotype. Pediatr Dermatol. 2000;17:12–20. [CrossRef] [PubMed] [Google Scholar]
  36. Walton JR, Martens MA, Pober BR. The proceedings of the 15th professional conference on Williams Syndrome. Am J Med Genet A. 2017;173:1159–1171. [CrossRef] [Google Scholar]
  37. Costantinides F, Castronovo G, Vettori E, Frattini C, Artero ML, Bevilacqua L, et al. Dental care for patients with end-stage renal disease and undergoing hemodialysis. Int J Dent. 2018;2018:9610892. [Google Scholar]

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