Open Access

Table IV

Pain assessment in evaluated studies.

Study Intervention Method of intervention Follow up Results Statistical significance
  Test group Control group     Test group Control group  
Sáez-Alcaide et al., 2020 [15] A topical gel of chitosan, 0.2% chlorhexidine, allantoin, and dexpanthenol. Placebo gel included all the components of the commercially available gel except chitosan, 0.2% chlorhexidine, allantoin, and dexpanthenol. 10-cm VAS score 48 hours and 7 days 2.56±1.19 3.25±1.6 p = 0.002
Pippi et al., 2016 [18] HDD Haemostatic sponge 0-10 subjective scale (Pain Score) An evening of surgery (PS T1) and the next morning over the phone (PS T2) and 5 ±1 days after at the moment of suture removal (PS T3). PS T1 (2.55 ± 2.16)
PS T2 (1.10 ± 1.94)
PS T3 (0)
PS T1 (2.30 ± 2.25)
PS T2 (1.60 ± 1.90)
PS T3 (0.30 ± 0.65)
PS T1 (p = 0.7263)
PS T2 (p = 0.3843)
PS T3 (p < 0.05)
Lope- Lopez et al., 2015 [16] Gel containing chlorhexidine, dexpanthenol, allantoin and chitosan (BP) gel BC oral rinse 10-cm VAS score 6 hours and 7 days 6.5±1.2 6.5±1.3 p = 0.0001

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