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Table I

Table depicting lesions that can present as palatal masses with differentiating features [29].

Lesions Differentiating features Histopathological features
Benign & malignant tumors
Epithelial origin: Squamous Cell Carcinoma (SCC)
Exophytic, proliferative growth with irregular borders and indurated base Crystal violet and Feulgen stains are superior in identifying the mitotic figures than H&E [2]
Salivary origin:
Mucoepidermoid carcinoma
Firm, painless swelling in the palate that is compressible Alcian blue and Mucicarmine stains are positive [3]
Pleomorphic adenoma Sometimes it has a blue/ red hue on the surface mimicking a mucocele [4] Pleomorphic adenoma stains positive for mucicarmine [3]
Naso-maxillary origin: Rubbery submucosal mass in the palate without surface ulceration
Malignancy of maxillary sinus The condition can present as palatal swelling/mass when there is infiltration of malignancy into the oral cavity with probable clinical symptoms (nasal obstruction, paraesthesia of zygomatic region) [5]
Infections
Actinomycosis
More common in immunocompromised individuals. Acute, painful palatal abscess with characteristic sulphur granules [6] Gomorimethenamine silver stain is useful in identifying the filaments of the organism [7]
Mucormycosis Chronic ulcer with raised margins, exposing the underlying bone [8] Gomorimethamine silver identifies the fungus. Further gram stain can be done to differentiate from Actinomycosis, which is a bacterial infection [9]

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