Comparative evaluation of effectiveness of 2% lignocaine hydrochloride with 1.5% potassium chloride versus 2% lignocaine hydrochloride with adrenaline bitartrate versus 2% lignocaine hydrochloride as local anaesthetic for adult patients undergoing surgical extraction of impacted mandibular third molars: a randomized controlled clinical study

Rinku Kalra; Shreyas Gupte; Thomson D'Cruz; Nidhi Pandey; Drishti Shah; Ranjana Patnaik

doi:10.1051/mbcb/2021017

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Volume 27 / No 4 (2021)

J Oral Med Oral Surg, 27 4 (2021) 55

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Original Research Article

Table I

Inter group comparison of Onset, duration, total amount/dose used, duration of surgery, number of injections and depth of anesthesia using VAS scale.

					95% confidence interval for mean

	Groups	Mean	Std. deviation	Std. error	Lower bound	Upper bound	Minimum	Maximum	F value	P value of one way ANOVA
Onset of analgesia (sec)	1	44.20	5.450	0.862	42.46	45.94	34	55
	2	102.60	9.803	1.550	99.46	105.74	76	120	470.702	0.000^**
	3	246.65	51.403	8.128	230.21	263.09	27	301
Duration of analgesia (min)	1	205.20	28.399	4.490	196.12	214.28	167	271
	2	222.43	61.369	9.703	202.80	242.05	154	456	110.759	0.000^**
	3	100.28	12.770	2.019	96.19	104.36	79	132
Total amount of dose used	1	2.20	0.608	0.096	2.01	2.39	2	4
	2	2.35	0.770	0.122	2.10	2.60	2	4	2.079	0.130#
	3	2.55	0.904	0.143	2.26	2.84	2	4
Duration of surgery (min)	1	15.10	4.460	0.705	13.67	16.53	5	26
	2	18.18	6.201	0.981	16.19	20.16	9	29	2.869	0.061#
	3	21.25	18.361	2.903	15.38	27.12	10	131
Number of injections required	1	1.10	0.304	0.048	1.00	1.20	1	2
	2	1.18	0.385	0.061	1.05	1.30	1	2	2.079	0.130#
	3	1.28	0.452	0.071	1.13	1.42	1	2
VAS	1	3.50	0.480	0.076	3.28	3.72	2	5
	2	3.73	0.599	0.095	3.53	3.92	2	4	6.452	0.002^**
	3	3.98	0.679	0.107	3.82	4.13	2	5

^* statistically significant difference (p < 0.05).

^**statistically highly significant difference (p < 0.01).

^# non significant difference (p > 0.05).

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