Med Buccale Chir Buccale
Volume 23, Number 4, December 2017
|181 - 183
|Article original / Original article
|22 December 2017
Short Case Report
Drug-induced oral mucous membrane pemphigoid: a case report
Head of Odontology and Oral Health, CHU of Bordeaux, France
2 Tissue Bioengineer, Unit 1026, University of Bordeaux, France
* Correspondence: email@example.com
Accepted: 1 March 2017
Observation: An 82-year-old patient treated with the antihistamine ebastine (Kestin®) for allergic rhinitis presented for gingival pain. The diagnosis of mucous membrane pemphigoid was suspected after a positive pinch test. Blood examinations highlighted AC anti-PBGA2, and the gingival biopsy showed an epithelioconjunctival delamination and the presence of anti-IgA antibody and C3 deposition along the basal of the membrane. Topical corticosteroid administration was initiated. The symptoms improved but elevated IgA and C3 levels persisted. He underwent a complete remission on cessation of ebastine treatment. Commentary: Mucous membrane pemphigoid is an autoimmune disease whose origin remains unclear. The aim of the treatment is to decrease the symptoms, but full recovery of the patients is exceptional. We report here a clinical case with symptom resolution because of the ebastine withdrawal. Ebastine can thus be suspected as a cause if a patient presents with oral symptoms of mucous membrane pemphigoid.
Key words: mucous membrane pemphigoid / toxidermy
© The authors, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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