Open Access

Table I

Clinical cases about isolated lichen planus of the lips reported in the literature from 1939 to 2019.

No. of case Article and year Age Sex Localization Clinical form Date of appearance Skin involvement Systemic pathologies Treatment Evolution with treatment
1 Whittle CH, 193913 69 Male Lower lip Plaque Genital mucosa No Mercure, arsenic, X-ray Stable
2 P. H. IT1 N, 19955 44 Male Lower lip Erosive 3 years no No Acitretin : neotigazon® 30 mg /day prednisone 15 mg /day, sun screen. Complete remission in 10 weeks
3 S. ALA.MN, 19966 51 Male Lower lip Reticular 9 months no No Betamethasone valerate® cream 0.1% / 2 weeks Complete remission in 3 months
4 D De Argila, 199711 51 Male Lower lip Erosive 11 years no No Chloroquine phosphate 25 mg/day Complete remission of symptoms in 6 months
5 Roberto Cecchi, 200210 43 Male Lower lip Reticular 7 months no No Betamethasone Dipropionate 0.5% ointment Complete remission in 1 months, no symptoms in 4 months
6 Chiang CT, 200212 36 Female Lower lip Erosive no No Prednisolone Remission
7 Yu Tc, 200317 44 Male Lower lip Erosive no Hypertension Clobetasol Remission
8 Donovan JC, 200518 51 Male Erosive no HCV-Hepatitis Tacrolimus Stable
9 Petruzzi M, 20074 52 Female Lower lip Hyperkeratosic 6 months No Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Complete remission
10 Petruzzi M, 20074 54 Male Lower lip Erosive, atrophic 10 months No Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Complete remission
11 Petruzzi M, 20074 73 Male Lower lip Erosive, atrophic 8 months HCV-Hepatitis Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Partial remission
12 Petruzzi M, 20074 49 Male Lower lip Erosive atrophic 4 months No Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Complete remission
13 Petruzzi M, 20074 52 Male Lower lip Hyperkeratosic 2 months No Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Complete remission
14 Petruzzi M, 20074 62 Male Lower lip Atrophic, erosive 8 months Diabetes Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Partial remission
15 Petruzzi M, 20074 74 Female Upper lip/ Lower lip Atrophic, erosive 10 months HCV-Hepatitis Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Complete remission
16 Petruzzi M, 20074 60 Male Lower lip Atrophic, erosive 3 months HCV-Hepatitis Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Complete remission
17 Petruzzi M, 20074 71 Male Upper lip / Lower lip Hyperkeratosic 4 months HCV-Hepatitis Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Complete remission
18 Petruzzi M, 20074 80 Female Upper lip / Lower lip Atrophic, erosive 6 months HCV-Hepatitis Clobetasol proprionate 0.05 % : cream 2/day, Tocopherol oil Complete remission
19 Johnson H, 200819 42 Female Lower lip Erosive - no No Tacrolimus Stable
20 Gencoglan G, 201115 56 Male Lower lip Erosive 2 months no No Imiquimod cream 5%, 2/day Complete remission, no recurrence in 18 months
21 Gencoglan G, 201115 61 Male Lower lip Erosive 6 years no No Imiquimod cream 5%, 2/day Amelioration within 2 weeks, recurrence within 6 months
22 Gencoglan G, 201115 65 Male Lower lip Reticular 11 years no No Imiquimod cream 5%, 2/day Remission within 2 weeks
23 Gencoglan G, 201115 22 Male Lower lip Reticular 4 years no No Imiquimod cream 5%, 2/day Healing in 2 weeks, no recurrence in 5 months
24 Sarika Holmukhe DNB, 20128 40 Male Lower lip Annular 3 months no No Tacrolimus 0.03 cream 3/day
25 Domingues E, 201220 44 Male Lower lip Erosive yes No Clobetasol Remission
26 Sugashima Y, 201221 32 Female Upper lip / Lower lip Annular no Allergy to zinc Tacrolimus Regression of the lesion
27 Dillip Kumar Samal, 20153 52 Male Lower lip Plaque 1 years no No Biopsy exerese No reccurence
28 Nuzzolo P, 20161 72 Male Upper lip Erosive no Liver insufficiency HCV-hepatitis Surgical excision Complete remission
29 Nuzzolo P, 20161 74 Male Upper lip / Lower lip Erosive no No Cortisone Stable
30 Ellie Choi, 20179 62 Female Lower lip Erosive 1 years no No Tacrolimus hydrocortisone vaseline, sun screen Complete remission, No reccurence in 2 years
31 FeiYan Yu, 201816 38 Female Lower lip Erosive 10 years no No TCM : “Qingwen Jiedu Kouyankang granules,” glucosides, antiinflammatory hormones/4 months Amelioration in 1 month, no recuurence in 5 months
32 Mathur M, 20192 44 Male Lower lip 4 months no No Betamethasone Diproprionate 0,5 % Amelioration in 15 days
33 Case report no. 1 34 Male Lower lip Erosive 3 months no Diabetes Clobetasol Complete remission in 5 months
34 Case report no. 2 33 Female Lower lip Erosive 8 years no No Betamethasone Remission in 7 months

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