One-day hospitalization in oral surgery : a 2-year comparative study

One-day hospitalization in oral surgery: a 2-year comparative study Kinz Bayet, Yacine Sifi, Maria-Pia Gondolfini, Timothée Gellee, Anthony Levy-Bohbot, Marc Levy, Aurélien Touboul, Patrick Guez, Alp Alantar 1 Hôpitaux de Paris, France 2 Functional Unit of Oral Surgery and IPES, Hôpital Max Fourestier, Centre hospitalier de Nanterre, France 3 Cardiology Service, Hôpital Max Fourestier, Centre hospitalier de Nanterre, France 4 Diabetology Service, Hôpital Max Fourestier, Centre hospitalier de Nanterre, France 5 Quality and Risk Delegation, Hôpital Max Fourestier, Centre hospitalier de Nanterre, France


Introduction
The increasing number of elderly patients with illnesses with cardiovascular and/or neurological comorbidities means that practitioners must adapt their practices to each individual case [1,2].A working group (cf.Annexes) Of the Max Fourestier Hospital (Nanterre) comprising Odontology service (Dr.H. Tran), Cardiology service (Dr.F. Digne), Diabetology service (Dr.M. Levy) Anesthesia Resuscitation service (Dr.R. Sabbagh) and the day Hospitalization Service (HDJ) of Max Fourestier Hospital (Nanterre) has put in place a care protocol for these patients considered "at risk."This protocol, according to the reports and recommendations of the la Société Française de Chirurgie Orale et de l'Evaluation des Pratiques Professionnelles (French Society for Oral Surgery and the Evaluation of professional practices) [3,4], aims to supervise and control interventions in these fragile patients.One-day surveillance is an alternative to complete hospitalization.The one-day surveillance allows the patient to return home in the best-case scenario or be admitted to hospital in case of complication [1,2,5].The objective of this 2-year comparative prospective observational study is to evaluate the rate (%) of perioperative complications in patients at risk with comorbidities and who were operated on in HDJ.

Outline of the study
This is a prospective study/evaluation that focuses on patients admitted to the Odontology service of Max Fourestier Hospital in 2014 and 2015.The mode of evaluation of therapeutics has been done in a pragmatic way, i.e., by leaving the treatments and interventions as they are usually practiced.

Population
The population consists of patients with multiple pathologies (co-occurrence of at least two chronic diseases over the same period) [2], whose general condition and/or the dental procedure indicates perioperative surveillance.Their free and informed consent is obtained beforehand.The state of their preoperative health is evaluated according to the American Society of Anesthetists (ASA) score ("Physical Status Score"), set up in 1941 by ASA [4,6] according to the severity of the systemic impairment.Patients included in the study are patients classified ASA 1, 2, and 3, the inclusion of ASA 4-6 patients is considered irrelevant.

Inclusion criteria
The general and local criteria, which may be associated or not, are as follows: General criteria -History of frequent discomfort because of hypoglycemia, epilepsy, asthma, and/or arrhythmia; high iatrogenic hemorrhagic risk: (direct oral anticoagulant), anti-vitamin K (AVK) with international normalized ratio (INR) >3, antiplatelet therapy; history of frequent falls; lack of compliance and therapeutic adherence; cognitive impairment; patients under guardianship or curatorship.The evaluation criterion is the rate (%) of local and/or general perioperative complications requiring a return to the dentist's chair or hospitalization.The local complications are hemorrhage, trauma, or pain.General complications malaise, fall, loss of consciousness, seizure, anaphylactic shock, asystole, or death.

Statistical analysis
The comparison of the overall rate (%) of the complications of the group studied with a control group of 78 randomly drawn cases with a table of numbers was made using a qualitative test (x 2 ).The patients in the control group were randomly selected from the same period as the study group.The interventions conducted out in the control group are comparable to the subjects tested.These are mainly dental extractions.The data were evaluated with an intent to treat.The declaration to the Commission nationale de l'informatique et des libertés (CNIL) [National Commission for Data Processing and Liberties] was made on July 24, 2015 (No. 1876016v0).

Results
The patient (68 interventions in 64 patients) and control (78 interventions in 78 patients) groups were comparable in age (61 ± 10 versus 68 ± 17 years, respectively) and sex (sexratio 1:1 in both groups).The interventions in both groups were comparable with the majority (>80%) having undergone dental extractions in the two groups.The average number of teeth extracted was otherwise comparable (2 ± 1 teeth per individual in each group).

Discussion
Multiple pathologies are often the rule in the elderly [2].The female prevalence (18.75%) of persons aged >65 years with multiple pathologies who consult dentists can be explained by higher life expectancy as well as the fact that women tend to care for their teeth more [7].
The way of evaluating treatment has been done in a pragmatic way, by leaving the treatments and interventions as they are usually practiced.The patient group, in particular, benefited from the specific strategies of at-risk patients: improving hemostasis and rinsing with tranexamic acid, in particular, for cardiovascular patients taking anticoagulants.
The rate of complications in the group of at-risk patients was statistically higher than in the control group and validates the indications that the researchers put in place in 2013.The vast majority of complications are hemorrhagic in patients with AVK confirming the increased hemorrhagic risk in elderly patients with AVK [8].The abnormal values of INR detected on the day of the intervention, allow for a better follow-up of these patients who will be referred to their treating physicians to titrate INR values [9].There was no need for full hospitalization, suggesting the cost-effectiveness of HDJ without posing risk to the patient, avoiding weekly hospitalization at higher cost.Surveillance in HDJ appears to be an alternative to hospitalization, allowing the patient to return home in better circumstances [1].This support appears particularly useful in patients with anticoagulants and/or antiplatelet agents, as the majority of complications are hemorrhagic.This strategy of HDJ is poorly developed in France when it comes to orofacial medicine but in other countries such as in Canada, where other noninvasive surgeries, such as unilateral parathyroidectomies, benefit from HDJ with proven results [5].The interest evoked by the authors is to ensure that the patient is comfortable and can safely return home with the best resources for the minimum cost.Noninvasive acts (prosthesis, descaling) are always possible in certain cases where precautions are taken [10].In the procedure proposed in this study, it is shown that HDJ ensures that immediate treatment is possible should perioperative complications arise and the patient can safely return home.
Following this study, a plan of action to improve the management of these patients was put in place with particular emphasis on: closer monitoring of patients taking anticoagulants in the dentist's chair and in HDJ, who are at higher risk, in particular, by improving the guidelines available for using the tranexamic acid protocol set up in 2012 and to take account of feedback (3); acquisition of a digital self-measuring device to check INR for patients under AVK.
Following this study, the evaluation criterion: "Rate (%) of local or general perioperative complications requiring full intervention or hospitalization of patients at risk for oral surgery with an HDJ" was proposed as a clinical practice indicator (CPI) in order to be registered in the Quality Account of the Max Fourestier institution.
These preliminary results allowed us to assess which patients required HDJ treatment at Max Fourestier Hospital.In this study, the rate of perioperative complications appears to be a relevant CPI.This study will allow researchers to follow the annual rate of these complications and allow them to adjust their actions to suit each patient at risk.In addition, this CPI will allow comparisons to be made between health facilities.Considering that no complications have resulted in complete hospitalization, HDJ has a place in the treatment protocols of oral surgery.