Open Access

Table II

Characteristics of selected studies.

Type of study Sex Number of BMS Number of controls Mean age of subjects ± SD (min–max) Type of quantification
Lopez-Jornet et al., 2020 Cross sectional BMS : 45W/6M Contrl : 26W/5M 51 31 Control : 58.3 ± 11.05 BMS : 59.12 ± 12.29 Total protein and uric acid: colorimetric kit for urine
Total IgA: ELISA
alpha amylase: commercial colorimetric kit
Lopez-Jornet et al., 2014 Cross sectional Control 13M and 17W
BMS 6M and 22W 28 30 Control 50 ± 17.2 BMS 58.8 ± 10.2 Spectrometry
Imura et al., 2016 Case–control Only women 15 30 BMS 55.20 ± 6.05 Control 52.27 ± 3.49 IgA : ELISA
Nosratzehi et al., 2017 Case–control Only women 30 30 BMS: 39.6 ± 13.3 Control : 39.5 ± 13.2 Cortisol : ELISA
Amylase : spectrophotometry
Amenabar et al., 2008 Case–control MS: 24W/6M, Control: ? 30 30 BMS: 61.6 ±10.7, Control : 63.7 ± 9.7 Radio immunoassay
De Moura et al., 2007 Case–control Each group 23W 1M 24 24 For all patients (45–84) ELISA
Aitken-Saavedra et al., 2021 Case–control Only women 40 40 BMS: 62.7 ± 10.8 (37–84), Control: 48.5 ± 12.35 (30–66) ELISA
Kim et al., 2012 Case–control Only women 15 14 BMS: 54.5 ± 6.3 Control: 70.6 ± 5.7 ELISA
Suh et al., 2009 Case–control Only women 40 20 BMS: 61.6 ± 10,1 Control: 65.1 ± 9.0 ELISA
Acharya et al., 2019 Case–control Only women 8 8 ? ELISA
Borelli et al., 2010 Case–control BMS 17 W 3M
Control 16 W 3 M 20 20 BMS : 69 (41–89), Control : 68–3 (41–77) ELISA (NGF / SP / Calprotectin)
spectrophotometry (Tryptase / MPO)
Bradford method proteins
Hershkovich et al., 2004 Case–control BMS 120 W 60 M
Control : 62 W 28 M 180 90 BMS : 58 ± 11, Control : 57 ± 16 (K) + (Na): spectrophotometry
Total protein: Lowry method
Amylase: Phadebas test
Lysozyme, IgM, IgG, IgA, and albumin radial immunodiffusion method
Boras et al., 2010 Case–control Only women 26 22 BMS: 65.69 (57–78), Control : 49.72 (24–82) Total protein and uric acid: colorimetric kit for urine
Total IgA: ELISA
alpha amylase: commercial colorimetric kit
Pekiner et al., 2009 Case–control BMS 19 W 11 M
Control 21 W 9M 30 30 BMS: 54.23 ± 12.78 Control: 50,87 ± 6,23 Cu, Mg and Zn: atomic absorbance spectrophotometry
Interleukins: ELISA
Henkin et al., 2012 Case–control BMS : 61 W 22 M        
Control : 43 W 12 M 83 55 BMS: 60 ± 4 Control: 49 ± 6 Spectrophotometry

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